Single-Use Bottom-Driven Mixing Bioreactor Bags BIOBGBRCF 撹拌システム用バッグ

BIOBGBRCF Single-Use Bottom-Driven Mixing Bioreactor Bags are designed to match
single-use bioreactors used in biophar-maceuticals. The product can be used for
scientific research, process development and commercial production of CHO, Vero, and MDCK cells.
• With RENOLIT 9101 multi-layer co-extrusion films, the fluid contact layer is ultra-low density polyethylene (ULDPE), which has good biocompatibility and chemical compatibility and contributes to a low level of extractable

• The ventilation tray contains 6 ventilation dial components, and the ventilation aperture is
available in 35 μm, 300 μm, and 1 mm, with good aperture uniformity. Free combinations of micro, medium, and macro sparges are supported to meet dif-ferent process requirements

• The impeller of 2000 L bioreactor bags are made of engineering-grade plastic Peek for high hardness. The N40E design has a lower shear force and a shorter mixing time

• Standard imported filters to ensure the integrity of bags

• Customized tubings

• Comprehensive validations with completed validation reports

Single-Use Top-Driven Bioreactor Bag
The core of the BIOBGBRCF 50L microbial fermentation system is the single-use microbial bioreactor bag designed to meet the stringent requirements of microbial fermentation. It is used for cultivating various organisms, including E-coli, pseudomonas, and yeast. The single-use microbial reactor bag is based on the proven design and materials of the BIOBGBRCF single-use bioreactor bags for mammalian cell culture.

• RENOLIT 9101 multilayer co-extruded film, ULDPE liquid contact layer, offering excellent biocompatibility and chemical compatibility while ensuring low levels of extractable content 

• The dual impeller design enables vigorous mixing of the culture, and the bottom magnetic coupling eliminates
external shafts, minimizing the risk of leakage

• All single-use microbial bioreactor bags are equipped with pressure sensors to maintain bag integrity during
demanding fermentation processes

• The vent filter is equipped with a condensation bag at the front end to integrate condensation, returning water
vapor from the gas back into the bag, ensuring the ventfilter remains unclogged

 

BIOBGBRTF Single-Use Top-Driven Bioreactor Bag
BIOBGBRTF Single-Use Top-Driven Bioreactor Bag is designed to match single-use top mechanical coupling
bioreactors used in biopharmaceuticals. The product can be used for scientific research, process development and
commercial production of CHO, Vero, and MDCK cells, etc.
• RENOLIT 9101 multilayer co-extruded film, ULDPE fluid contact layer, offering excellent biocompatibility and
chemical compatibility while ensuring low levels of extractable content
• The porous-frit microsparge column is designed from ultra-high molecular weight polyethylene (UHMW-PE), with
pore sizes ranging from 20-40 μm. The generated bubbles possess a high surface area ratio and enhanced oxygen
transfer. UHMW-PE exhibits outstanding impact resistance, wear resistance, chemical corrosion resistance,
physiological inertness, adaptability, and hydrophobicity
• The macro-perforated microporous membrane is a dispersed aeration disc based on film. Laser-drilled to
maintain uniform pore size, various specifications such as 0.178mm, 0.233mm, 0.368mm, 0.445mm, 0.582mm are
available, tailored with specific apertures and quantities for each bag specification
• Equipped with imported filters to ensure bag integrity
• All pipelines can be flexibly customized
• Fully validated, complete validation reports can be provided